The Hendo Family is one of the 10 Great Families, and is led by Hendo Lok Bloodmadder. It is the Great Family with the least influence and also has the smallest amount of Rankers. This is due to a pact that Bloodmadder made with the 100th Floor Guardian in exchange for eternal life, that curses Hendo's children to a short life.

Though the Hendo Family is the least influential, its members still uphold an ironclad set of rules, and Bloodmadder’s position within the clan is absolute. The Rankers that uphold the Hendo Family are all Hendo’s adopted sons and daughters.